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In enzymology, a 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase () is an enzyme that catalyzes the chemical reaction: : 2-C-methyl-D-erythritol 4-phosphate + CTP diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol Image:MEP.png|2-C-methylerythritol 4-phosphate Image:CTP chemical structure.png|Cytidine triphosphate Image:4-diphosphocytidyl-2-C-methylerythritol.png|4-diphosphocytidyl-2-C-methylerythritol (CDP-ME) Thus, the two substrates of this enzyme are CTP and 2-C-methyl-D-erythritol 4-phosphate, whereas its two products are diphosphate and 4-diphosphocytidyl-2-C-methylerythritol. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). This enzyme participates in isoprenoid biosynthesis. It catalyzes the third step of the MEP pathway; the formation of CDP-ME (4-diphosphocytidyl-2C-methyl-D-erythritol) from CTP and MEP (2C-methyl-D-erythritol 4-phosphate). The isoprenoid pathway is a well known target for anti-infective drug development. == Nomenclature == The systematic name of this enzyme class is CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase. This enzyme is also called: * MEP cytidylyltransferase * CDP-ME synthetase It is normally abbreviated IspD. It is also referenced by the open reading frame YgbP. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase」の詳細全文を読む スポンサード リンク
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